Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology

نویسندگان

  • Kazuhito Satou
  • Makiko Shimoji
  • Hinako Tamotsu
  • Ayaka Juan
  • Noriko Ashimine
  • Misuzu Shinzato
  • Claudia Toma
  • Toshitsugu Nohara
  • Akino Shiroma
  • Kazuma Nakano
  • Kuniko Teruya
  • Yasunobu Terabayashi
  • Shun Ohki
  • Nobuo Koizumi
  • Shou Okano
  • Toshihiko Suzuki
  • Takashi Hirano
چکیده

Here, we report the complete genome sequences of low-passage virulent and high-passage avirulent variants of pathogenic Leptospira interrogans serovar Manilae strain UP-MMC-NIID, a major causative agent of leptospirosis. While there were no major differences between the genome sequences, the levels of base modifications were higher in the avirulent variant.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2015